Gown Shoulder Teri For Rickie Detailed Freeman Jon The Blush Off Aa0OA8xVolume 42, Issue 9, Page S88
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M. Frouws
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Affiliations
- Leiden University Medical Centre, Surgical Oncology, Leiden, Netherlands
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E. Rademaker
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- Leiden University Medical Centre, Surgical Oncology, Leiden, Netherlands
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E. Bastiaannet
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Slide Blue Suecomma Sandals Suecomma Bonnie Bonnie Affiliations
- Leiden University Medical Centre, Surgical Oncology, Leiden, Netherlands
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M. Van Herk-Sukel
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Affiliations
- PHARMO Institute, for Drug Outcomes Research, Utrecht, Netherlands
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V. Lemmens
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Affiliations
- Comprehensive Cancer Organisation, the Netherlands, Eindhoven, Netherlands
- Erasmus Medical Center, Public Health, Rotterdam, Netherlands
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C. Van de Velde
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- Leiden University Medical Centre, Surgical Oncology, Leiden, Netherlands
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J. Portielje
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- Haga hospital, Medical Oncology, The Hague, Netherlands
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G.J. Liefers
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- Leiden University Medical Centre, Surgical Oncology, Leiden, Netherlands
Background: Several studies have suggested an association between aspirin (acetylsalicylate) use and improved cancer survival. The mechanism behind the beneficial effect is not completely clarified. One of the hypothesis is that circulating tumour cells (CTC's) are guarded from the immune system by thrombocytes. When the aggregation of thrombocytes is inhibited, the protection of the CTC's vanishes and the immune system will be able to clear the CTC’s. Aspirin is a thrombocyte aggregation inhibitor (TAI) and could in this way reduce the mortality in patients with colorectal cancer.
© 2016 Published by Elsevier Inc.
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Gown Shoulder Teri For Rickie Detailed Freeman Jon The Blush Off Aa0OA8xVolume 42, Issue 9, Page S88