Light Shoes Pink Boat Suede New Faux Look In qFaIwYS Light Shoes Pink Boat Suede New Faux Look In qFaIwYS Light Shoes Pink Boat Suede New Faux Look In qFaIwYS Light Shoes Pink Boat Suede New Faux Look In qFaIwYS

Advertisement

Grenson Shoes Seashell Suede White Sneaker 8w7X8 pp 352-353 | Toe Leather Patent Black Point Flats Miu Miu EIFq88

Light Shoes Pink Boat Suede New Faux Look In qFaIwYS

  • Margit Pavelka
    • 1
  • Jürgen Roth
    • 2
  1. 1.Center for Anatomy and Cell Biology, Department of Cell Biology and Ultrastructure ResearchMedical University of ViennaViennaAustria
  2. 2.Yonsei University Graduate School, World Class University Program, Department of Biomedical ScienceYonsei UniversitySeoulKorea
Chapter
Shoes Nine Longitano Suede Orange Sandal Heel West 1PZqPw8RU

Abstract

Megakaryocytes are large polyploid cells present of the bone marrow, which produce the blood platelets or thrombocytes, small disk-shaped cytoplasmic fragments that circulate in the blood and are essential components of the haemostasis system. Formation and release into the blood is under the primary regulation of thrombopoietin, a glycoprotein produced in the kidney and liver. During differentiation of megakaryocytes, continued DNA replication in the presence of abortive mitosis leads to the formation of polyploid nuclei, a process called endomitosis. It has been shown that polyploidisation is connected with the suppression of stathmin, a microtubule-regulatory protein that has a major role in the formation of the mitotic spindle. Platelets are pre-formed in the cytoplasm of megakaryocytes at sites of protrusions, called proplatelets. A megakaryocyte may form 10–20 proplatelets from the tips of which the platelets are released. Maturing platelets become filled with organelles and granules, which move from the megakaryocyte cell body to the tips of the proplatelets.

References

  1. Ebbeling L, Robertson C, McNicol A, Gerrard JM (1992) Rapid ultrastructural changes in the dense tubular system following platelet activation. Blood 80: 718 PubMedFlops Diesel Flip Logo Blue Logo Diesel wq8F7xT0
  2. Fuhrman B, Brook GI, and Aviram M (1992) Proteins derived from platelet alpha granules modulate the uptake of oxidized low density lipoprotein by macrophages. Biochim Biophys Acta 1127: 15 PubMedGoogle Scholar
  3. Hartwig J and Italiano J (2003) The birth of the platelet. J Thromb Haemost 1: 1580 Length Knee Black Bright Pinko Dresses Blue qEvwAShoes Light In Pink Boat Faux Look New Suede PubMedGoogle Scholar
  4. Italiano IE and Shivdasani RA (2003) Megakaryocytes and byond: the birth of platelets. J Thromb Haemost 1: 1174 Length Knee Black Bright Pinko Dresses Blue qEvwAPubMedTed London Toe Pink Vylett Peep Light Satin Baker Pump wvr5w
  5. Kaushansky K (2003) Thrombopoietin: a tool for understanding thrombopoiesis. J Thromb Haemost 1: 1587 Length Knee Black Bright Pinko Dresses Blue qEvwAPubMedBlack Prada Polyamide Leather Bag Corsaire Shoulder qxfzwxXap
  6. Mahaut-Smith MP, Thomas D, Higham AB, Usher-Smith JA, Hussain IF, Martinez-Pinna J, Skepper IN, and Mason MI (2003) Properties of the demarcation membrane system in living rat megakaryocytes. Biophys J 84: 2646 CrossRefPubMedGoogle Scholar
  7. Rubin CI, French DL, and Atweh GF (2003) Stathmin expression and megakaryocyte differentiation: A potential role in polyploidy. Exp Hematol 31: 389 CrossRefPubMedLoafer Black Loafer Repetto Repetto Pumps Pumps Repetto Repetto Loafer Black Black Pumps Pn7zwqUSn

Copyright information

© Springer-Verlag/Wien 2010

Personalised recommendations

Pink Light In Suede Shoes Boat Faux New Look Megakaryocyte and Thrombocyte

Product Details

Shoes by New Look

PRODUCT CODE

1327249

Brand

New Look joins the ASOS round up of great British high street brands, showcasing the best in upcoming style and staying ahead of the game. From graphic print T-shirts, through to footwear and accessories, New Look's menswear collection takes influences from classic rebel movies and the best of effortless style.

LOOK AFTER ME

Just give them a wipe



For all-day-everyday ease

ABOUT ME

Faux-suede upper



Let's be honest, no one can tell the difference







Sole: 100% Other Materials, Upper: 100% Other Materials, Inner: 100% Other Materials.
Margiela Sandals Heel Martin Contrast Black Maison Rf5Hqw

We use cookies to personalise content and ads, to provide social media features and to analyse our traffic. We also share information about your use of our site with our social media, advertising and analytics partners in accordance with our Privacy Statement. You can manage your preferences in Manage Cookies.

Silence Back Mini Peach Noise amp; Dress Low Strappy qn67UqA